Yankees vs. Astros Computer Picks, MLB Odds and Betting Lines for October 20, 2022

Two of the best teams in the American League dial it up again in the Championship Series with a lot on the line in Game 2.

It's Thursday, October 20, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for sports bettors across the United States.

With our MLB best bets, probabilities, and odds featured each and every day, check out our best betting picks for Wednesday's MLB games below.

Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.

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Best MLB Bet Today

Yankees vs. Astros, 7:37PM ET

Following the Yankees' loss in Game 1 yesterday, they will turn to Luis Severino in Game 2, and the Astros should be licking their chops. In two starts against Houston this season, Severino pitched six innings max and earned a Loss in both games. The last time Severino took the mound in the playoffs, he gave up eight hits and three earned runs in just 5.2 innings pitched to the Guardians. It's safe to say he hasn't had his best stuff in the postseason just yet. The Astros will look to Framber Valdez, who has been brilliant in the playoffs. The Astros are 2-0 in his two starts, and Valdez has given up just six hits and two earned runs in 10.2 innings pitched in the postseason, striking out 14 batters in the process. We think Houston protects home field in this one.

BET: Astros RUN LINE (+150). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

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Best MLB Prop Today

Yuli Gurriel had came up huge in Game 1, going yard in the 6th inning against the Yankees to give his Astros the lead. We think he may have the magic again tonight, facing a pitcher in Severino that he has had success against over the course of his career. Gurriel has six hits against Severino in 17 career at-bats, good for a .353 average. He has two homers now in the postseason, and he'll have a great chance to add to that in Game 2.

BET: Yuli Gurriel 1+ HR (+950). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

⚾️ Yankees vs. Astros Predictions
✍🏼 Betting Preview: Yankees vs. Astros

Visit our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section.

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Best MLB Same Game Parlay Today

There are numerous different ways you can wager on MLB games in 2022, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $200 no matter what promo to guarantee a big cash.

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🔥 Astros RUN LINE
🔥 Gurriel HR

*All odds and lines correct at time of publishing