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Penrith Panthers vs. Wests Tigers Prediction: Panthers Predicted to Win Saturday's NRL Round 21 Matchup [7/26/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Saturday's Penrith Panthers vs Wests Tigers matchup.
NRL action continues on Saturday at 3:30AM ET as the Wests Tigers take on the Penrith Panthers at Panthers Stadium.
Based on the latest simulation results, Dimers' proven NRL model (see Dimers Pro for full access) projects the Panthers as the most likely winner of today's game.
For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Tigers vs. Panthers predictions page.
Panthers vs. Tigers Prediction: Who Will Win Round 21 Game?
Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NRL matchup between the Tigers and Panthers 10,000 times as part of our NRL predictions coverage.
Our independent predictive model gives the Panthers an 82% chance of beating the Tigers.
According to our model, the Panthers (-12.5) have a 52% chance of covering the spread, while the over/under total of 47.5 has a 55% chance of staying under.
Tigers vs. Panthers Odds
We have researched the best NRL odds in America for this game, which are listed here:
| Bet Type | Tigers | Panthers |
|---|---|---|
| H2H (Moneyline) | +325 | -476 |
| Line (Spread) | +12.5 (-115) | -12.5 (-110) |
| Total | o47.5 (-115) | u47.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Panthers vs. Tigers Game-Day Updates and Essential Details
Saturday's Australian rugby league game between the Panthers and Tigers at Panthers Stadium is scheduled to commence at 3:30AM ET.
- Who: Wests Tigers vs. Penrith Panthers
- Date: Saturday, July 26, 2025
- Time: 3:30AM ET/12:30AM PT
- Venue: Panthers Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Dimers.com's full preview of Saturday's Tigers vs. Panthers matchup includes our prediction, picks and the latest betting odds.
Before making any Tigers vs. Panthers picks, be sure to check out the latest NRL predictions and betting advice from Dimers Pro.
Conclusion
We predict the Panthers, with an 82% win probability, will likely beat the Tigers on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Tigers vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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