Western Michigan vs. Michigan State prediction: Why Michigan State is favored to win in college football Week 1, 2025

Michigan State will square off with Western Michigan in college football action at Spartan Stadium on Friday, commencing at 7:00PM ET.

Based on the latest simulation results, Dimers' advanced college football model predicts Michigan State as the most likely winner of today's game.

For a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Western Michigan vs. Michigan State predictions page.

Western Michigan vs. Michigan State prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the result of Western Michigan vs. Michigan State 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Michigan State a 93% chance of defeating Western Michigan. Our predicted final score has Michigan State winning 35-13.

According to our model, the bookmakers have got it right, and Western Michigan and Michigan State each have a 50% chance of covering the spread, while the 50.5-point over/under has a 52% chance of going over.

Western Michigan vs. Michigan State odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type	Western Michigan	Michigan State
Spread	+21.5 (-108)	-21.5 (-110)
Moneyline	+1060	-1800
Total	o50.5 (-105)	u50.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Western Michigan vs. Michigan State picks and best bets

Our model's strongest edge in today's Western Michigan vs. Michigan State matchup is on the spread.

Our expert predictions, matched against the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Western Michigan vs. Michigan State game-day updates and essential details

Friday's college football game between Michigan State and Western Michigan at Spartan Stadium is scheduled to begin at 7:00PM ET.

• Who: Western Michigan vs. Michigan State
• Date: Friday, August 29, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Spartan Stadium

Dimers.com's in-depth preview of Friday's Western Michigan vs. Michigan State matchup includes our prediction, picks and the latest betting odds.

Before making any Western Michigan vs. Michigan State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Michigan State, with a 93% win probability, will likely beat Western Michigan on Friday.

AI and automation have enhanced this article to quickly deliver accurate Western Michigan vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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