Western Illinois vs. Illinois prediction: Why Illinois is favored to win in college football Week 1, 2025

Illinois will face Western Illinois in college football action at Memorial Stadium on Friday, beginning at 7:30PM ET.

Based on updated simulation results, Dimers' proven college football model projects Illinois as the most likely winner of today's game.

For a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Western Illinois vs. Illinois predictions page.

Western Illinois vs. Illinois prediction: Who will win, cover the spread?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Western Illinois vs. Illinois 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Illinois a 100% chance of beating Western Illinois. Our predicted final score has Illinois winning 53-6.

According to our model, the bookmakers have got it right, and Western Illinois and Illinois each have a 50% chance of covering the spread, while the over/under total of 63.5 points has a 57% chance of going over.

Western Illinois vs. Illinois odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type	Western Illinois	Illinois
Spread	+48.5 (-102)	-48.5 (-110)
Moneyline	+8000	-100000
Total	o63.5 (-110)	u63.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Western Illinois vs. Illinois picks and best bets

Our model's biggest edge in today's Western Illinois vs. Illinois matchup is on the spread.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Western Illinois vs. Illinois game-day updates and essential details

Friday's college football game between Illinois and Western Illinois at Memorial Stadium is scheduled to commence at 7:30PM ET.

• Who: Western Illinois vs. Illinois
• Date: Friday, August 29, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Memorial Stadium

Dimers.com's full preview of Friday's Western Illinois vs. Illinois matchup includes our prediction, picks and the latest betting odds.

Before making any Western Illinois vs. Illinois picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Illinois, with a 100% win probability, will likely beat Western Illinois on Friday.

AI and automation have enhanced this article to quickly deliver accurate Western Illinois vs. Illinois insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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