West Virginia vs. Kansas prediction: Kansas favored to win in college football Week 4, 2025

Kansas and West Virginia will clash in Week 4 college football action at David Booth Kansas Memorial Stadium on Saturday, with kickoff at 6:00PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts Kansas as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive West Virginia vs. Kansas predictions page.

West Virginia vs. Kansas prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of West Virginia vs. Kansas 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Kansas a 73% chance of defeating West Virginia. Our predicted final score has Kansas winning 31-21.

According to our model, West Virginia (+12.5) has a 57% chance of covering the spread, while the over/under total of 54.5 points has a 52% chance of going over.

West Virginia vs. Kansas odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	West Virginia	Kansas
Spread	+12.5 (-106)	-12.5 (-110)
Moneyline	+375	-455
Total	o54.5 (-105)	u54.5 (-110)

All odds are correct at the time of publication and are subject to change.

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West Virginia vs. Kansas picks and best bets

Our model's strongest edge in today's West Virginia vs. Kansas matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

West Virginia vs. Kansas game-day updates and essential details

Saturday's college football matchup between Kansas and West Virginia at David Booth Kansas Memorial Stadium is scheduled to begin at 6:00PM ET.

• Who: West Virginia vs. Kansas
• Date: Saturday, September 20, 2025
• Time: 6:00PM ET/3:00PM PT
• Venue: David Booth Kansas Memorial Stadium

Dimers' in-depth preview of Saturday's West Virginia vs. Kansas matchup includes our prediction, picks and the latest betting odds.

Before making any West Virginia vs. Kansas picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Kansas, with a 73% win probability, will likely beat West Virginia on Saturday.

AI and automation have enhanced this article to quickly deliver accurate West Virginia vs. Kansas insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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