Nationals vs. Cardinals Prediction: St. Louis Predicted to Win Wednesday's MLB Matchup [7/9/2025]

MLB action continues on Wednesday at 7:45PM ET as the Washington Nationals take on the St. Louis Cardinals at Busch Stadium.

The Cardinals will send Andre Pallante (5-4, 4.10 ERA) to the mound, while the Nationals have opted for MacKenzie Gore (3-8, 3.10 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Cardinals as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Nationals-Cardinals game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cardinals' chance of winning at 54%, with the Nationals at 46%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Nationals vs. Cardinals predictions page.

Cardinals vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Nationals and Cardinals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Cardinals a 54% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 66% chance of covering the run line, while the over/under total of 7.5 runs has an equal 50-50 chance of hitting.

Nationals vs. Cardinals Odds [7/9/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Nationals	Cardinals
Run Line	+1.5 (-194)	-1.5 (+165)
Moneyline	+120	-140
Total	o7.5 (-118)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Nationals vs. Cardinals Picks and Best Bets

Our model's strongest edge in today's Nationals vs. Cardinals matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Nationals vs. Cardinals Game-Day Updates and Essential Details

Wednesday's MLB action between the Cardinals and Nationals at Busch Stadium is scheduled to commence at 7:45PM ET.

• Who: Washington Nationals vs. St. Louis Cardinals
• Date: Wednesday, July 9, 2025
• Time: 7:45PM ET/4:45PM PT
• Venue: Busch Stadium

Dimers.com's in-depth preview of Wednesday's Nationals vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Nationals vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Plus, with sports betting in Missouri launching on December 1, 2025, Dimers has you covered with the latest news and the best MO sports betting promos.

Conclusion

We predict the Cardinals, with a 54% win probability, will likely beat the Nationals on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest projections for the World Series, American League, National League and each division.