Nationals vs. Cardinals Prediction: St. Louis Predicted to Win Tuesday's MLB Matchup [7/8/2025]

The St. Louis Cardinals will face the Washington Nationals in MLB action at Busch Stadium on Tuesday, beginning at 7:45PM ET.

The Cardinals will start Sonny Gray (8-3, 3.51 ERA), pitting him against Jake Irvin (7-3, 4.71 ERA) for the Nationals.

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Nationals vs. Cardinals predictions page.

Cardinals vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Tuesday's MLB game between the Nationals and Cardinals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Cardinals a 66% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 53% chance of covering the run line, while the over/under total of 8.5 runs has a 55% chance of staying under.

Nationals vs. Cardinals Odds [7/8/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Nationals	Cardinals
Run Line	+1.5 (+100)	-1.5 (-111)
Moneyline	+200	-235
Total	o8.5 (+104)	u8.5 (-128)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Nationals vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Nationals vs. Cardinals matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Nationals vs. Cardinals Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Cardinals and Nationals at Busch Stadium is scheduled to begin at 7:45PM ET.

• Who: Washington Nationals vs. St. Louis Cardinals
• Date: Tuesday, July 8, 2025
• Time: 7:45PM ET/4:45PM PT
• Venue: Busch Stadium

Dimers.com's in-depth preview of Tuesday's Nationals vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Nationals vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Plus, with Missouri sports betting launching on December 1, 2025, Dimers has everything you need—from the latest news and the best pre-registration offers in MO.

Conclusion

We predict the Cardinals, with a 66% win probability, will likely beat the Nationals on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest projections for the World Series, American League, National League and each division.