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Nationals vs. Cardinals Prediction: St. Louis Predicted to Win Thursday's MLB Matchup [7/10/2025]

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Written by Dave Garofolo

Our expert prediction for Thursday's Washington Nationals vs St. Louis Cardinals matchup.

Washington Nationals-St. Louis Cardinals Predictions and Game Preview.
Busch Stadium sets the stage for the MLB matchup between the Washington Nationals and St. Louis Cardinals this Thursday.

The St. Louis Cardinals and Washington Nationals are scheduled to meet in MLB action at Busch Stadium on Thursday, starting at 7:45PM ET.

The Cardinals will start Miles Mikolas (4-6, 5.26 ERA), while the Nationals are going with Michael Soroka (3-6, 5.40 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

For further insights into Thursday's matchup, including best bets and picks, visit our interactive Nationals vs. Cardinals predictions page.

Cardinals vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Thursday's MLB matchup between the Nationals and Cardinals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Cardinals a 55% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 62% chance of covering the run line, while the over/under total of 9 runs has a 53% chance of staying under.

 

Nationals vs. Cardinals Odds [7/10/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Nationals Cardinals
Run Line +1.5 (-172) -1.5 (+146)
Moneyline +124 -140
Total o9 (+100) u9 (-115)

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Cardinals Picks and Best Bets

Our model's strongest edge in today's Nationals vs. Cardinals matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Nationals vs. Cardinals Game-Day Updates and Essential Details

Thursday's MLB game between the Cardinals and Nationals at Busch Stadium is scheduled to begin at 7:45PM ET.

Dimers.com's comprehensive preview of Thursday's Nationals vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Nationals vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Plus, with sports betting in Missouri set to launch on December 1, 2025, Dimers has you covered with the latest news and the best pre-registration offers in MO.

Conclusion

We predict the Cardinals, with a 55% win probability, will likely beat the Nationals on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest predictions for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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