Nationals vs. Mets prediction: Mets favored to win Friday's MLB matchup [9/19/2025]

The New York Mets and Washington Nationals will lock horns in MLB action at Citi Field on Friday, starting at 7:10PM ET.

Brandon Sproat (0-1, 2.25 ERA) will be on the bump for the Mets, while the Nationals have opted for Andrew Alvarez (1-0, 1.15 ERA).

Based on the latest simulation results, Dimers' advanced MLB model predicts the Mets as the most likely winner of today's game.

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Nationals vs. Mets predictions page.

Mets vs. Nationals prediction: Who will win, cover the run line?

Using powerful machine learning and data analysis, we have simulated the result of Friday's MLB matchup between the Nationals and Mets 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Mets a 66% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 53% chance of covering the run line, while the 8.5-run over/under has a 55% chance of going over.

Nationals vs. Mets odds [9/19/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Nationals	Mets
Run Line	+1.5 (-112)	-1.5 (-105)
Moneyline	+191	-220
Total	o8.5 (-120)	u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Mets picks and best bets

Our model's biggest edge in today's Nationals vs. Mets matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

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Nationals vs. Mets game-day updates and essential details

Friday's MLB game between the Mets and Nationals at Citi Field is scheduled to begin at 7:10PM ET.

• Who: Washington Nationals vs. New York Mets
• Date: Friday, September 19, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Citi Field

Dimers' comprehensive preview of Friday's Nationals vs. Mets matchup includes our prediction, picks and the latest betting odds.

Before making any Nationals vs. Mets picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mets, with a 66% win probability, will likely beat the Nationals on Friday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Mets insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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