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Nationals vs. Twins Prediction: Minnesota Predicted to Win Friday's MLB Matchup [7/25/2025]
Our expert prediction for Friday's Washington Nationals vs Minnesota Twins matchup.

The Minnesota Twins will square off with the Washington Nationals in MLB action at Target Field on Friday, starting at 8:10PM ET.
The Twins will have Zebby Matthews (1-2, 6.26 ERA) as their starting pitcher, while the Nationals have opted for MacKenzie Gore (4-9, 3.60 ERA).
Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.
For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Nationals vs. Twins predictions page.
Twins vs. Nationals Prediction: Who Will Win, Cover the Run Line?
Using trusted machine learning and data, we have simulated the result of Friday's MLB matchup between the Nationals and Twins 10,000 times as part of our MLB predictions coverage.
Our famous predictive model gives the Twins a 58% chance of beating the Nationals.
According to our model, the Nationals (+1.5) have a 62% chance of covering the run line, while the over/under total of 8.5 runs has a 51% chance of going over.
Nationals vs. Twins Odds [7/25/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
Bet Type | Nationals | Twins |
---|---|---|
Run Line | +1.5 (-166) | -1.5 (+145) |
Moneyline | +140 | -158 |
Total | o8.5 (-106) | u8.5 (-110) |
All odds are correct at the time of publication and are subject to change.
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Nationals vs. Twins Picks and Best Bets
Our model's biggest edge in today's Nationals vs. Twins matchup is on the moneyline.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets Today
Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.
Nationals vs. Twins Game-Day Updates and Essential Details
Friday's MLB game between the Twins and Nationals at Target Field is scheduled to start at 8:10PM ET.
- Who: Washington Nationals vs. Minnesota Twins
- Date: Friday, July 25, 2025
- Time: 8:10PM ET/5:10PM PT
- Venue: Target Field
Dimers.com's in-depth preview of Friday's Nationals vs. Twins matchup includes our prediction, picks and the latest betting odds.
Before making any Nationals vs. Twins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Twins, with a 58% win probability, will likely beat the Nationals on Friday.
AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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