Nationals vs. Dodgers Prediction: Dodgers Predicted to Win Saturday's MLB Matchup [6/21/2025]

The Los Angeles Dodgers will face the Washington Nationals in MLB action at Dodger Stadium on Saturday, beginning at 10:10PM ET.

The Dodgers will send Dustin May (4-4, 4.46 ERA) to the mound, up against Jake Irvin (5-3, 4.23 ERA) for the Nationals.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Dodgers as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Nationals-Dodgers game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Dodgers are more likely to win, while the Nationals have a lower chance of victory."

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Nationals vs. Dodgers predictions page.

Dodgers vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Saturday's MLB matchup between the Nationals and Dodgers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Dodgers a 68% chance of beating the Nationals.

According to our model, the Dodgers (-1.5) have a 52% chance of covering the run line, while the over/under total of 10 runs has a 56% chance of staying under.

Nationals vs. Dodgers Odds [6/21/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Nationals	Dodgers
Run Line	+1.5 (+118)	-1.5 (-134)
Moneyline	+228	-270
Total	o10 (-107)	u10 (-110)

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Dodgers Picks and Best Bets

Our model's biggest edge in today's Nationals vs. Dodgers matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Nationals vs. Dodgers Game-Day Updates and Essential Details

Saturday's MLB action between the Dodgers and Nationals at Dodger Stadium is scheduled to start at 10:10PM ET.

• Who: Washington Nationals vs. Los Angeles Dodgers
• Date: Saturday, June 21, 2025
• Time: 10:10PM ET/7:10PM PT
• Venue: Dodger Stadium

Dimers.com's in-depth preview of Saturday's Nationals vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Nationals vs. Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Dodgers, with a 68% win probability, will likely beat the Nationals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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