Nationals vs. Reds Prediction: Cincinnati Predicted to Win Saturday's MLB Matchup [5/3/2025]

MLB action continues on Saturday at 6:40PM ET as the Washington Nationals square off with the Cincinnati Reds at Great American Ball Park.

The Reds will have Nick Lodolo (3-2, 2.25 ERA) as their starting pitcher, while the Nationals have opted for Trevor Williams (1-3, 5.70 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Reds as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Washington-Cincinnati game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Reds are more likely to win, while the Nationals have a lower chance of victory."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Nationals vs. Reds predictions page.

Reds vs. Nationals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's MLB game between the Nationals and Reds 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Reds a 62% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 56% chance of covering the run line, while the over/under total of 9 runs has a 57% chance of staying under.

Nationals vs. Reds Odds [5/3/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Nationals	Reds
Run Line	+1.5 (-126)	-1.5 (+110)
Moneyline	+164	-185
Total	o9 (+100)	u9 (-118)

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Reds Picks and Best Bets

Our model's strongest edge in today's Nationals vs. Reds matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Nationals vs. Reds Game-Day Updates and Essential Details

Saturday's MLB game between the Reds and Nationals at Great American Ball Park is scheduled to commence at 6:40PM ET.

• Who: Washington Nationals vs. Cincinnati Reds
• Date: Saturday, May 3, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Great American Ball Park

Dimers.com's in-depth preview of Saturday's Nationals vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Washington vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Reds, with a 62% win probability, will likely beat the Nationals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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