Nationals vs. Cubs prediction: Why Cubs are favored to win Sunday's MLB matchup [9/7/2025]

MLB action continues on Sunday at 2:20PM ET as the Washington Nationals lock horns with the Chicago Cubs at Wrigley Field.

The Cubs will send Drew Pomeranz (2-1, 2.40 ERA) to the mound, while the Nationals will counter with Andrew Alvarez (1-0, 0.00 ERA).

Based on the latest simulations, Dimers' advanced MLB model predicts the Cubs as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Nationals-Cubs game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Cubs with a win probability of 64%, while the Nationals have 36%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Nationals vs. Cubs predictions page.

Cubs vs. Nationals prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB matchup between the Nationals and Cubs 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Cubs a 64% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 56% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of going over.

Nationals vs. Cubs odds [9/7/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Nationals	Cubs
Run Line	+1.5 (-133)	-1.5 (+116)
Moneyline	+168	-190
Total	o7.5 (+103)	u7.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Nationals vs. Cubs picks and best bets

Our model's strongest edge in today's Nationals vs. Cubs matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Nationals vs. Cubs game-day updates and essential details

Sunday's MLB matchup between the Cubs and Nationals at Wrigley Field is scheduled to commence at 2:20PM ET.

• Who: Washington Nationals vs. Chicago Cubs
• Date: Sunday, September 7, 2025
• Time: 2:20PM ET/11:20AM PT
• Venue: Wrigley Field

Dimers.com's comprehensive preview of Sunday's Nationals vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Nationals vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cubs, with a 64% win probability, will likely beat the Nationals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Nationals vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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