Virginia Tech vs. South Carolina prediction: South Carolina favored to win in college football Week 1, 2025

South Carolina and Virginia Tech will lock horns in college football action at Mercedes-Benz Stadium on Sunday, with kickoff at 3:00PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts South Carolina as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Virginia Tech-South Carolina game," said Ryan Leaver from Dimers.

"After accounting for recent updates and other variables, our prediction shows South Carolina with a win probability of 63%, while Virginia Tech has 37%."

For a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Virginia Tech vs. South Carolina predictions page.

Virginia Tech vs. South Carolina prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the result of Virginia Tech vs. South Carolina 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives South Carolina a 63% chance of defeating Virginia Tech. Our predicted final score has South Carolina winning 27-22.

According to our model, Virginia Tech (+6.5) has a 55% chance of covering the spread, while the 51.5-point over/under has a 53% chance of going over.

Virginia Tech vs. South Carolina odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type	Virginia Tech	South Carolina
Spread	+6.5 (+102)	-6.5 (-124)
Moneyline	+220	-260
Total	o51.5 (-110)	u51.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Virginia Tech vs. South Carolina picks and best bets

Our model's biggest edge in today's Virginia Tech vs. South Carolina matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Virginia Tech vs. South Carolina game-day updates and essential details

Sunday's college football action between South Carolina and Virginia Tech at Mercedes-Benz Stadium is scheduled to start at 3:00PM ET.

• Who: Virginia Tech vs. South Carolina
• Date: Sunday, August 31, 2025
• Time: 3:00PM ET/12:00PM PT
• Venue: Mercedes-Benz Stadium

Dimers.com's full preview of Sunday's Virginia Tech vs. South Carolina matchup includes our prediction, picks and the latest betting odds.

Before making any Virginia Tech vs. South Carolina picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict South Carolina, with a 63% win probability, will likely beat Virginia Tech on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Virginia Tech vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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