Venus Williams vs. Karolina Muchova prediction, odds, picks for US Open 2025

Venus Williams and Karolina Muchova will lock horns in the first round of the US Open 2025 on Monday.

Based on updated simulations, Dimers' advanced tennis model projects Karolina Muchova as the most likely winner of the match.

For a closer look at Monday's match, including best bets and picks, visit our interactive Williams vs. Muchova predictions page.

Williams vs. Muchova prediction: Who will win and advance to the Second Round?

Using powerful machine learning and data analysis, we have simulated the outcome of Monday's Williams-Muchova women's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Muchova a 90% chance of winning against Williams in the US Open 2025.

Additionally, Muchova has an 85% chance of winning the first set. The simulations also show Williams (+6.5) has a 53% chance of covering the games spread, while the under 18.5 games has a 54% chance of hitting, according to our model.

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Venus Williams vs. Karolina Muchova odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Williams	Muchova
Moneyline	+860	-1667
First Set	+500	-833
Game Spread	-6.5 (-112)	+6.5 (-118)
Total Games	o18.5 (+105)	u18.5 (-130)

All odds are correct at the time of publication and are subject to change.

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Williams vs. Muchova picks and best bets

Our model's biggest edge in today's Williams vs. Muchova match is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Williams vs. Muchova updates and essential details

The US Open 2025 match between Venus Williams and Karolina Muchova is scheduled to begin on Monday at 7:00PM ET.

• Who: Venus Williams vs. Karolina Muchova
• Date: Monday, August 25, 2025
• Approx. Time: 7:00PM ET/4:00PM PT
• Tournament: US Open Women's Singles 2025
• Round: First round

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's comprehensive preview of Monday's Williams vs. Muchova match includes our prediction, picks and the latest betting odds.

Before making any Venus Williams vs. Karolina Muchova picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Karolina Muchova, with a 90% win probability, will likely beat Venus Williams at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Williams vs. Muchova insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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