Troy vs. Clemson prediction: Why Clemson is favored to win in college football Week 2, 2025

Clemson will face Troy in Week 2 college football action at Memorial Stadium on Saturday, with kickoff at 3:30PM ET.

Based on the latest simulations, Dimers' proven college football model predicts Clemson as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Troy vs. Clemson predictions page.

Troy vs. Clemson prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the result of Troy vs. Clemson 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Clemson a 98% chance of defeating Troy. Our predicted final score has Clemson winning 41-11.

According to our model, Clemson (-19.5) has a 62% chance of covering the spread, while the 53.5-point over/under has a 56% chance of staying under.

Troy vs. Clemson odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Troy	Clemson
Spread	+19.5 (-115)	-19.5 (-115)
Moneyline	+2500	-1450
Total	o53.5 (-120)	u53.5 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Troy vs. Clemson picks and best bets

Our model's biggest edge in today's Troy vs. Clemson matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Troy vs. Clemson game-day updates and essential details

Saturday's college football game between Clemson and Troy at Memorial Stadium is scheduled to start at 3:30PM ET.

• Who: Troy vs. Clemson
• Date: Saturday, September 6, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Memorial Stadium

Dimers.com's in-depth preview of Saturday's Troy vs. Clemson matchup includes our prediction, picks and the latest betting odds.

Before making any Troy vs. Clemson picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Sports betting deal available for NCAAF Saturday

To make the most of Saturday's exciting day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that scores you $300 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict Clemson, with a 98% win probability, will likely beat Troy on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Troy vs. Clemson insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on College Football

Keep up with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the latest projections for the national title game and major conferences.