Blue Jays vs. Rays prediction: Why Toronto is favored to win Monday's MLB matchup [9/15/2025]

MLB action continues on Monday at 7:35PM ET as the Toronto Blue Jays lock horns with the Tampa Bay Rays at George M. Steinbrenner Field.

Joe Boyle (1-3, 5.40 ERA) will get the ball for the Rays, pitting him against Trey Yesavage (0-0, 0.00 ERA) for the Blue Jays.

Based on the latest simulations, Dimers' proven MLB model predicts the Blue Jays as the most likely winner of today's game.

For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Blue Jays vs. Rays predictions page.

Rays vs. Blue Jays prediction: Who will win, cover the run line?

Using powerful machine learning and data analysis, we have simulated the result of Monday's MLB game between the Blue Jays and Rays 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Blue Jays a 54% chance of defeating the Rays.

According to our model, the Rays (+1.5) have a 60% chance of covering the run line, while the over/under total of 8 runs has a 52% chance of going over.

Blue Jays vs. Rays odds [9/15/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Blue Jays	Rays
Run Line	-1.5 (+135)	+1.5 (-156)
Moneyline	-126	+110
Total	o8 (-116)	u8 (+100)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Blue Jays vs. Rays picks and best bets

Our model's biggest edge in today's Blue Jays vs. Rays matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Blue Jays vs. Rays game-day updates and essential details

Monday's MLB matchup between the Rays and Blue Jays at George M. Steinbrenner Field is scheduled to commence at 7:35PM ET.

• Who: Toronto Blue Jays vs. Tampa Bay Rays
• Date: Monday, September 15, 2025
• Time: 7:35PM ET/4:35PM PT
• Venue: George M. Steinbrenner Field

Dimers' in-depth preview of Monday's Blue Jays vs. Rays matchup includes our prediction, picks and the latest betting odds.

Before making any Blue Jays vs. Rays picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Sports betting deal available for Maryland sports fans

To make the most of Monday's exciting day of sports, headlined by college football MNF, check out details on the latest Bet365 bonus code "DIMERS" that secures $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict the Blue Jays, with a 54% win probability, will likely beat the Rays on Monday.

AI and automation have enhanced this article to quickly deliver accurate Blue Jays vs. Rays insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.