Blue Jays vs. Royals prediction: Toronto favored to win Saturday's MLB matchup [9/20/2025]

The Kansas City Royals will take on the Toronto Blue Jays, in what is expected to be a tight MLB game, at Kauffman Stadium on Saturday, commencing at 7:10PM ET.

Noah Cameron (8-7, 2.98 ERA) will start for the Royals, while the Blue Jays will counter with Shane Bieber (3-1, 3.72 ERA).

Based on updated simulations, Dimers' proven MLB model predicts the Blue Jays as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Blue Jays vs. Royals predictions page.

Royals vs. Blue Jays prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the outcome of Saturday's MLB matchup between the Blue Jays and Royals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Blue Jays a 53% chance of defeating the Royals.

According to our model, the Royals (+1.5) have a 59% chance of covering the run line, while the 8-run over/under has a 55% chance of going over.

Blue Jays vs. Royals odds [9/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Blue Jays	Royals
Run Line	-1.5 (+126)	+1.5 (-150)
Moneyline	-132	+115
Total	o8 (-112)	u8 (+100)

All odds are correct at the time of publication and are subject to change.

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Blue Jays vs. Royals picks and best bets

Our model's strongest edge in today's Blue Jays vs. Royals matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

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Blue Jays vs. Royals game-day updates and essential details

Saturday's MLB matchup between the Royals and Blue Jays at Kauffman Stadium is scheduled to commence at 7:10PM ET.

• Who: Toronto Blue Jays vs. Kansas City Royals
• Date: Saturday, September 20, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Kauffman Stadium

Dimers' full preview of Saturday's Blue Jays vs. Royals matchup includes our prediction, picks and the latest betting odds.

Before making any Blue Jays vs. Royals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Blue Jays, with a 53% win probability, will likely beat the Royals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Blue Jays vs. Royals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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