Blue Jays vs. Astros Prediction: Houston Predicted to Win Tuesday's MLB Matchup [4/22/2025]

The Houston Astros will face the Toronto Blue Jays in MLB action at Daikin Park on Tuesday, starting at 8:10PM ET.

Ronel Blanco (1-2, 6.48 ERA) will get the ball for the Astros, up against Chris Bassitt (2-0, 0.77 ERA) for the Blue Jays.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Toronto-Houston game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Astros with a win probability of 53%, compared to 47% for the Blue Jays."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Blue Jays vs. Astros predictions page.

Astros vs. Blue Jays Prediction: Who Will Win?

Using powerful machine learning and statistical analysis, we have simulated the result of Tuesday's MLB game between the Blue Jays and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Astros a 53% chance of defeating the Blue Jays.

According to our model, the 8-run over/under also has an equal 50-50 chance of hitting.

Blue Jays vs. Astros Odds [4/22/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Blue Jays	Astros
Moneyline	-116	+102
Total	o8 (-110)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Blue Jays vs. Astros Picks and Best Bets

Our model's biggest edge in today's Blue Jays vs. Astros matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Blue Jays vs. Astros Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Astros and Blue Jays at Daikin Park is scheduled to start at 8:10PM ET.

• Who: Toronto Blue Jays vs. Houston Astros
• Date: Tuesday, April 22, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Tuesday's Blue Jays vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Toronto vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Astros, with a 53% win probability, will likely beat the Blue Jays on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Blue Jays vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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