Blue Jays vs. Reds prediction: Why Cincinnati is favored to win Labor Day MLB matchup [9/1/2025]

MLB action continues on Monday at 1:10PM ET as the Toronto Blue Jays lock horns with the Cincinnati Reds at Great American Ball Park.

The Reds will have Hunter Greene (5-4, 2.80 ERA) as their starting pitcher, while the Blue Jays are going with Chris Bassitt (11-7, 4.14 ERA).

Based on updated simulation results, Dimers' advanced MLB model predicts the Reds as the most likely winner of today's game.

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Blue Jays vs. Reds predictions page.

Reds vs. Blue Jays prediction: Who will win, cover the run line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Monday's MLB matchup between the Blue Jays and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Reds a 52% chance of defeating the Blue Jays.

According to our model, the Blue Jays (+1.5) have a 66% chance of covering the run line, while the 7.5-run over/under has a 55% chance of going over.

Blue Jays vs. Reds odds [9/1/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Blue Jays	Reds
Run Line	+1.5 (-205)	-1.5 (+170)
Moneyline	+105	-120
Total	o7.5 (-115)	u7.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Blue Jays vs. Reds picks and best bets

Our model's biggest edge in today's Blue Jays vs. Reds matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Blue Jays vs. Reds game-day updates and essential details

Monday's MLB matchup between the Reds and Blue Jays at Great American Ball Park is scheduled to commence at 1:10PM ET.

• Who: Toronto Blue Jays vs. Cincinnati Reds
• Date: Monday, September 1, 2025
• Time: 1:10PM ET/10:10AM PT
• Venue: Great American Ball Park

Dimers.com's full preview of Monday's Blue Jays vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Blue Jays vs. Reds picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Reds, with a 52% win probability, will likely beat the Blue Jays on Monday.

AI and automation have enhanced this article to quickly deliver accurate Blue Jays vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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