Titans vs. Bills Week 2 Prediction and Odds - Sep 19, 2022

The Buffalo Bills take on the Tennessee Titans in NFL Week 2 action at Highmark Stadium on Monday, commencing at 7:15PM ET.

Dimers' top betting picks for Titans vs. Bills, plus game predictions, betting odds and touchdown scorer probabilities, are featured in this article.

This Tennessee vs. Buffalo betting preview is presented by FanDuel Sportsbook, which is currently offering a great No Sweat First Bet deal up to $1,000 for new users.

Who will win Titans vs. Bills?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Monday's Titans-Bills NFL game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Bills an 80% chance of winning against the Titans in Week 2 of the NFL season.

More: Full Betting Guide for Titans vs. Bills

Titans vs. Bills Current Odds

• Spread: Bills -10 (-105), Titans +10 (-105)
• Moneyline: Bills -435, Titans +375
• Total: Over/Under 47 (-110/-110)

Point Spread, Moneyline and Over/Under

The Bills are listed as -10 favorites versus the Titans, with -105 at PointsBet the best odds currently available.

For the underdog Titans (+10) to cover the spread, DraftKings Sportsbook has the best odds currently on offer at -105.

DraftKings Sportsbook currently has the best moneyline odds for the Bills at -435, which means you can risk $435 to win $100, for a total payout of $535, if they get the W.

On the other hand, PointsBet currently has the best moneyline odds for the Titans at +375, where you can put down $100 to profit $375, earning a total payout of $475, if they win.

The Over/Under for total points scored sits at 47 with Caesars Sportsbook, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you can bet with in your state for the best NFL odds and lines.

According to DimersBOT, the Titans (+10) are a 53% chance of covering the spread, while the 47-point Over/Under is a 52% chance of going Over.

More: Free Prop Picks

Best Bets for Titans vs. Bills

• Spread: Titans +10 @ -105 via DraftKings Sportsbook (53% probability)
• Moneyline: Bills @ -435 via DraftKings Sportsbook (80% probability)
• Total: Over 47 @ -110 via Caesars Sportsbook (52% probability)

Dimers' best bets are based on complex modeling and wagering expertise to bring you the best possible plays 24/7.

Titans vs. Bills Prediction

Dimers.com's predicted final score for Tennessee vs. Buffalo at Highmark Stadium in Week 2 has the Bills winning 28-19.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Titans-Bills matchup in Week 2, including pregame predictions, free picks, and live win probabilities.

Titans vs. Bills Player Props

Who will score the first touchdown in Titans vs. Bills? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Titans and Bills, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop bets for Monday's game.

According to DimersBOT, Tennessee's Derrick Henry is most likely to score the first TD in Titans vs. Bills.

DimersBOT gives Henry a 12.6% chance of getting in for six first at Highmark Stadium, while the Titans RB is a 52.7% chance of scoring an anytime touchdown.

Scroll down for our full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Tennessee Titans

• Derrick Henry: 12.6% probability
• Robert Woods: 5.6% probability
• Austin Hooper: 3.5% probability
• Geoff Swaim: 3.3% probability
• Treylon Burks: 3.3% probability

Buffalo Bills

• Stefon Diggs: 12.0% probability
• Josh Allen: 9.3% probability
• Dawson Knox: 8.6% probability
• Zack Moss: 8.2% probability
• Devin Singletary: 8.0% probability

Anytime Touchdown Scorer Probabilities

Tennessee Titans

• Derrick Henry: 52.7% probability
• Robert Woods: 27.1% probability
• Austin Hooper: 18.8% probability
• Kyle Philips: 17.8% probability
• Geoff Swaim: 17.5% probability

Buffalo Bills

• Stefon Diggs: 50.5% probability
• Josh Allen: 41.2% probability
• Dawson Knox: 38.4% probability
• Zack Moss: 37.9% probability
• Devin Singletary: 36.9% probability

Titans-Bills Projected Player Stats

Of the starting quarterbacks, the Titans' Ryan Tannehill is projected for 214 passing yards. The Bills' Josh Allen is expected to throw for a whopping 278 yards.

Titans Starting QB

• Ryan Tannehill: 214 projected yards

Bills Starting QB

• Josh Allen: 278 projected yards

Titans Rushing

• Derrick Henry: 101 projected yards
• Hassan Haskins: 14 projected yards
• Ryan Tannehill: 14 projected yards

Bills Rushing

• Devin Singletary: 51 projected yards
• Josh Allen: 40 projected yards
• Zack Moss: 25 projected yards

Titans Receiving

• Treylon Burks: 43 projected yards
• Kyle Philips: 41 projected yards
• Robert Woods: 41 projected yards
• Nick Westbrook-Ikhine: 28 projected yards
• Austin Hooper: 26 projected yards

Bills Receiving

• Stefon Diggs: 73 projected yards
• Dawson Knox: 36 projected yards
• Isaiah McKenzie: 29 projected yards
• Jamison Crowder: 28 projected yards
• Devin Singletary: 13 projected yards

Don't forget, DimersBOT updates often, so keep checking this article for any changes to our betting analysis before Titans vs. Bills on Monday September 19, 2022.

Titans vs. Bills 2022

The NFL Week 2 matchup between the Bills and Titans at Highmark Stadium is scheduled to commence at 7:15PM ET.

• Who: Tennessee Titans vs. Buffalo Bills
• Date: Monday September 19, 2022
• Time: 7:15PM ET / 4:15PM PT
• Venue: Highmark Stadium

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