Three NFL futures bets to make before Week 1 on the 49ers, Bengals and Bills

As the summer winds down and the NFL season is upon us, it's our last chance to bet on NFL futures before the regular season comes into play. This league is shaped every week and an injury or setback can flip a playoff or division race on its head early

Just like we've done with our NFL Win Total Predictions and NFL Playoff Predictions, we're breaking down some of the best value in NFL futures markets, form division winners to Super Bowl LX champions.

With the end of the summer also comes the end of our time with the Dimers Summer Interns who have been crushing content and cashing bets with us throughout these past couple of months. To send them off, we asked them to fire up the Dimers Pro NFL Futures, where they each found one bet with value the model recommends.

Maybe they'll send us all off with some winning tickets come the NFL Playoffs - if you want to see all of our NFL futures predictions where even more value awaits, get a Dimers Pro football season pass for 50% off with our exclusive FOOTBALL promo code.

Use promo code FOOTBALL for 50% off a year of Dimers Pro.

The three NFL futures bets you need to make before Week 1

49ers to win the NFC West (+160 on BetMGM)

The top team I’m eying in the futures market is the San Francisco 49ers. Dimers' data projects the 49ers with the most wins in the NFC this season at just over 10.5. They’re also projected to win the NFC West this season with a 46.4% probability, making them just one of two teams we project under 50% as a favorite.

The Niners were the most injured team in football last season. It seems highly improbable that they will have the worst injury luck in the league again and they should be much better as a team if their injury luck regresses to the middle of the pack as a healthy Christian McCaffrey changes the entire offense.

Speaking of injury concerns, the Niners' prime contender in this division is the Rams. The Rams hope Matt Stafford can stay healthy this season as he nears 40.

Currently you can get San Francisco at +160 to win the division at BetMGM, and that feels like a gift considering the numbers. The implied probability of +160 is about 38.5%, while our projections have the Niners winning the NFC West 46.4% of the time. 

MORE: Dimers Staff make Super Bowl LX picks, Bold Predictions for 2025 NFL season

This is an edge of nearly 8 percent! Highly recommend betting the Niners to win the NFC West.

Another bet I’m targeting for the 49ers is that they will win the NFC. They have the third-best odds in the conference at +950, which indicates an implied probability of 9.5 percent; however, our projections have the Niners winning the conference 12.8 percent of the time.

This is an edge of over 3 percent! That’s tremendous value and actionable information you can take advantage of. - Tony Reyes

Bengals to win the AFC (+1200 on DraftKings)

According to Dimers models, there's a 9.0% probability that should have every bettor's interest

The odds are at +1200 for Cincinnati taking home the AFC crown, and based on Dimers' 9.0% projection, fair odds should be +1000. Beside the obvious value, there are two reasons why you should invest in Who Dey: Joe Burrow and schedule.

Coming off a Comeback Player of the Year award, Joe Burrow is in prime position for another Super Bowl run. Riches of receivers, running backs, and a surefire offense looks like a blueprint that will require opponents to score 30 points to win the game. To aid even more in the offensive side of the ball, two young receivers in Jermaine Burton and Mitchell Tinsley have arrived. With very impressive preseason showings, it already looks like the best receiver room in the NFL got even better. Joe Burrow has an embarrassment of riches - if the offensive line can block, Cincinnati has the team to make another 2021 type run.

Early season frustrations have plagued the Bengals the past few seasons. This team seems to fall flat early. as displayed by recent starts of  2-2 and 1-3.

That could change this year as HC Zach Taylor played starters hard in the preseason. This season Cincy’s schedule has a mix of elite and underperforming teams from last year. To begin the season, 2 of the first 3 games are against teams that did not win 5 games in 2024. Every season is different, but the Bengals have to beat the lesser teams. If these two advantages help this team, this bet can take you all the way to the cash line. - Derrick Inabinnett

Bills to win Super Bowl LX (+750 on FanDuel)

The Buffalo Bills are a contender year in and year out as long as returning MVP quarterback Josh Allen is under center, and I think this year is the year they finally get over the hump and win it all.

Dimers gives the Bills a 12% chance to win the Super Bowl, only behind the Ravens who are at 15.1%, and predicts their win total at 11.6, the highest win projections of all NFL teams according to the win model. You can currently get the Bills to win the Super Bowl at +750 on FanDuel, and I think there is unreal value with that line, especially considering the Bills are as short as +600 and favored on some books.

There is no doubt the AFC East is incredibly weak this year and should no doubt be dominated by Buffalo. The Patriots are improving but still a young and not that skilled team, the Jets are entering a year with almost a completely different looking regime, and the already mediocre Miami Dolphins got a notably worse roster entering this regular season. The Bills are currently around -300 to win the division and Dimers gives them a 74.6% chance to do that, so it is very likely the Bills will at least get to the playoffs.

From there, it is likely the Bills have to take down their usual playoff speedbumps in the Ravens and the Chiefs. I don’t think the Chiefs beat the Bills this year, and I think this is the year that Josh further establishes himself in the top quarterback conversation with a AFC championship and then a Super Bowl to cap it off. - Bradley Barrett

The NFL Futures Parlay

Think DimersBOT and the interns are in sync?

You have to make a slight adjustment as the Bills can't win the Super Bowl and the Bengals win the AFC Championship, but you can take the Bengals to reach the AFC title game.

Roll a parlay that features these three results with he above mentioned adjustment for crazy odds of +15713, returning $785.68 off a $5 bet over at FanDuel Sportsbook.

That would be one wild way to close out a Dimers summer internship!

For more from Dimers on the 2025 NFL season and beyond, learn how to get your football season pass for 50% off today.

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Dimers' 2025 NFL Season Betting Resources

• NFL Predictions: Our data-backed previews for every game, every day
• NFL Best Bets: Our Top Picks for every individual matchup
• Best NFL Props: Player edges and projections from our predictive analytics model
• NFL Futures Odds: Who will win Super Bowl LX?
• NFL Betting News: The latest promos, storylines and more around the league

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