Texas Southern vs. Mississippi Valley State prediction: Why Texas Southern is favored to win in college football Week 5, 2025

Mississippi Valley State and Texas Southern will clash in Week 5 college football action at Rice-Totten Stadium on Saturday, with kickoff at 5:00PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts Texas Southern as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Texas Southern vs. Mississippi Valley State predictions page.

Texas Southern vs. Mississippi Valley State prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the outcome of Texas Southern vs. Mississippi Valley State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Texas Southern an 83% chance of beating Mississippi Valley State. Our predicted final score has Texas Southern winning 31-18.

According to our model, the bookies have got it right, and Texas Southern and Mississippi Valley State each have a 50% chance of covering the spread, while the over/under total of 46.5 points has a 55% chance of staying under.

Texas Southern vs. Mississippi Valley State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Texas Southern	Mississippi Valley State
Spread	-13.5 (-110)	+13.5 (-110)
Moneyline	-520	+400
Total	o46.5 (-115)	u46.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Texas Southern vs. Mississippi Valley State picks and best bets

Our model's biggest edge in today's Texas Southern vs. Mississippi Valley State matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Texas Southern vs. Mississippi Valley State game-day updates and essential details

Saturday's college football action between Mississippi Valley State and Texas Southern at Rice-Totten Stadium is scheduled to begin at 5:00PM ET.

• Who: Texas Southern vs. Mississippi Valley State
• Date: Saturday, September 27, 2025
• Time: 5:00PM ET/2:00PM PT
• Venue: Rice-Totten Stadium

Dimers' comprehensive preview of Saturday's Texas Southern vs. Mississippi Valley State matchup includes our prediction, picks and the latest betting odds.

Before making any Texas Southern vs. Mississippi Valley State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict Texas Southern, with an 83% win probability, will likely beat Mississippi Valley State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Texas Southern vs. Mississippi Valley State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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