Rangers vs. Astros prediction: Close contest projected after new data released for Tuesday's MLB matchup [9/16/2025]

The Houston Astros will square off with the Texas Rangers, in what is expected to be a close MLB game, at Daikin Park on Tuesday, commencing at 8:10PM ET.

AJ Blubaugh (3-1, 2.46 ERA) will be the starting pitcher for the Astros, while the Rangers are going with Merrill Kelly (12-7, 3.21 ERA).

Based on updated simulation results, Dimers' proven MLB model projects an equal chance for both the Astros and Rangers to win today's game.

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Rangers vs. Astros predictions page.

Astros vs. Rangers prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the result of Tuesday's MLB matchup between the Rangers and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model can't split the two teams, giving both the Rangers and Astros a 50% chance of winning the game.

According to our model, the Astros (+1.5) have a 63% chance of covering the run line, while the 7.5-run over/under has a 58% chance of going over.

Rangers vs. Astros odds [9/16/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Rangers	Astros
Run Line	-1.5 (+145)	+1.5 (-164)
Moneyline	-115	+100
Total	o7.5 (-115)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Rangers vs. Astros picks and best bets

Our model's strongest edge in today's Rangers vs. Astros matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Rangers vs. Astros game-day updates and essential details

Tuesday's MLB action between the Astros and Rangers at Daikin Park is scheduled to start at 8:10PM ET.

• Who: Texas Rangers vs. Houston Astros
• Date: Tuesday, September 16, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers' in-depth preview of Tuesday's Rangers vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Rangers vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict a close game between the Rangers and Astros on Tuesday, with each team having a 50% chance of winning.

AI and automation have enhanced this article to quickly deliver accurate Rangers vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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