Titans vs. Texans prediction: Houston favored to win in NFL Week 4, 2025

NFL Week 4 action continues on Sunday at 1:00PM ET as the Tennessee Titans look to defy the odds against the Houston Texans at NRG Stadium.

Based on the latest simulation results, Dimers' advanced NFL model projects the Texans as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Titans-Texans game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Texans with a win probability of 77%, while the Titans have 23%."

This gameday Titans vs. Texans betting preview builds on my Titans vs. Texans prediction that was posted earlier in the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Titans vs. Texans predictions page.

Titans vs. Texans Predictions

Since our Titans-Texans predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Titans and Texans 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Texans a 77% chance of defeating the Titans in Week 4 of the NFL season. Our predicted final score has the Texans winning 23-16.

According to our model, the Titans (+7) have a 54% chance of covering the spread, while the over/under total of 39.5 points has an equal 50-50 chance of hitting.

Titans vs. Texans odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type	Titans	Texans
Spread	+7 (-105)	-7 (-115)
Moneyline	+340	-400
Total	o39.5 (-110)	u39.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Titans vs. Texans picks and best bets

Our model's biggest edge in today's Titans vs. Texans matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Titans vs. Texans TD scorers

Who will score an anytime touchdown in Titans vs. Texans?

According to our model, Tennessee's Tony Pollard is most likely to score the first TD in Titans vs. Texans.

Our projections give Pollard an 11.2% chance of getting in for six first at NRG Stadium, while the Titans running back is a 37.6% chance of scoring an anytime touchdown.

First touchdown scorer predictions

Tennessee Titans

Player	First TD Probability
Tony Pollard (RB)	11.2%
Calvin Ridley (WR)	6.3%
Elic Ayomanor (WR)	5.4%

Houston Texans

Player	First TD Probability
Nico Collins (WR)	11.0%
Nick Chubb (RB)	10.9%
Woody Marks (RB)	7.2%

Anytime touchdown scorer predictions

Tennessee Titans

Player	Anytime TD Probability
Tony Pollard (RB)	37.6%
Calvin Ridley (WR)	23.2%
Elic Ayomanor (WR)	20.2%

Houston Texans

Player	Anytime TD Probability
Nico Collins (WR)	38.0%
Nick Chubb (RB)	37.9%
Woody Marks (RB)	27.0%

Titans vs Texans player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Titans and Texans. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Titans-Texans page now to access every player prop projection.

Titans vs. Texans quarterbacks

Of the starting quarterbacks, the Titans' Cam Ward is projected to throw for fewer yards than the Texans' C.J. Stroud.

Titans rushing

Tony Pollard, Julius Chestnut and Cam Ward are projected to be the leading rushers for the Titans.

Player	Position
Tony Pollard	RB
Julius Chestnut	RB
Cam Ward	QB

Texans rushing

Nick Chubb, Woody Marks and C.J. Stroud are expected to lead the Texans in rushing yards.

Player	Position
Nick Chubb	RB
Woody Marks	RB
C.J. Stroud	QB

Titans receiving

Calvin Ridley, Elic Ayomanor, Chig Okonkwo, Tyler Lockett and Chimere Dike are projected to top the receiving yards for the Titans.

Player	Position
Calvin Ridley	WR
Elic Ayomanor	WR
Chig Okonkwo	TE
Tyler Lockett	WR
Chimere Dike	WR

Texans receiving

Nico Collins, Christian Kirk, Dalton Schultz, Xavier Hutchinson and Jayden Higgins are projected to lead the Texans in receiving yards.

Player	Position
Nico Collins	WR
Christian Kirk	WR
Dalton Schultz	TE
Xavier Hutchinson	WR
Jayden Higgins	WR

Titans vs. Texans game-day updates and essential details

The NFL Week 4 game between the Texans and Titans at NRG Stadium is scheduled to start at 1:00PM ET.

• Who: Tennessee Titans vs. Houston Texans
• Date: Sunday, September 28, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: NRG Stadium

Dimers' comprehensive preview of Sunday's Titans vs. Texans matchup includes our prediction, picks and the latest betting odds.

Before making any Titans vs. Texans picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Texans, with a 77% win probability, will likely beat the Titans in Week 4 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Titans vs. Texans insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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