Rays vs. Astros Prediction: Houston Predicted to Win Saturday's MLB Matchup [5/31/2025]

The Houston Astros will take on the Tampa Bay Rays in MLB action at Daikin Park on Saturday, commencing at 4:10PM ET.

The Astros will have Colton Gordon (0-0, 5.52 ERA) as their starting pitcher, pitting him against Zack Littell (4-5, 3.98 ERA) for the Rays.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Tampa Bay-Houston game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Astros are more likely to win, while the Rays have a lower chance of victory."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Rays vs. Astros predictions page.

Astros vs. Rays Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Saturday's MLB game between the Rays and Astros 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Astros a 58% chance of defeating the Rays.

According to our model, the Rays (+1.5) have a 61% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

Rays vs. Astros Odds [5/31/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rays	Astros
Run Line	+1.5 (-185)	-1.5 (+155)
Moneyline	+110	-130
Total	o8.5 (-110)	u8.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Rays vs. Astros Picks and Best Bets

Our model's strongest edge in today's Rays vs. Astros matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Rays vs. Astros Game-Day Updates and Essential Details

Saturday's MLB matchup between the Astros and Rays at Daikin Park is scheduled to begin at 4:10PM ET.

• Who: Tampa Bay Rays vs. Houston Astros
• Date: Saturday, May 31, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Saturday's Rays vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Tampa Bay vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Astros, with a 58% win probability, will likely beat the Rays on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Rays vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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