Rays vs. Guardians prediction: Why Cleveland is favored to win Tuesday's MLB matchup [8/26/2025]

The Cleveland Guardians and Tampa Bay Rays will meet in MLB action at Progressive Field on Tuesday, starting at 6:40PM ET.

The Guardians will send Parker Messick (0-0, 1.35 ERA) to the mound, while the Rays are going with Shane Baz (8-10, 5.22 ERA).

Based on the latest simulations, Dimers' advanced MLB model projects the Guardians as the most likely winner of today's game.

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Rays vs. Guardians predictions page.

Guardians vs. Rays prediction: Who will win?

Using innovative machine learning and statistical analysis, we have simulated the result of Tuesday's MLB matchup between the Rays and Guardians 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Guardians a 51% chance of beating the Rays.

According to our model, the over/under total of 7.5 runs has a 53% chance of going over.

Rays vs. Guardians odds [8/26/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Rays	Guardians
Moneyline	+102	-115
Total	o7.5 (-117)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Rays vs. Guardians picks and best bets

Our model's strongest edge in today's Rays vs. Guardians matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Rays vs. Guardians game-day updates and essential details

Tuesday's MLB action between the Guardians and Rays at Progressive Field is scheduled to commence at 6:40PM ET.

• Who: Tampa Bay Rays vs. Cleveland Guardians
• Date: Tuesday, August 26, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Progressive Field

Dimers.com's comprehensive preview of Tuesday's Rays vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Rays vs. Guardians picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Guardians, with a 51% win probability, will likely beat the Rays on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Rays vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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