Rays vs. White Sox prediction: Why Tampa Bay is favored to win Thursday's MLB matchup [9/11/2025]

MLB action continues on Thursday at 2:10PM ET as the Tampa Bay Rays take on the Chicago White Sox at Rate Field.

The White Sox will have Shane Smith (5-7, 3.95 ERA) as their starting pitcher, while the Rays will counter with Ian Seymour (3-1, 2.89 ERA).

Based on updated simulations, Dimers' proven MLB model predicts the Rays as the most likely winner of today's game.

For further insights into Thursday's matchup, including best bets and picks, visit our interactive Rays vs. White Sox predictions page.

White Sox vs. Rays prediction: Who will win, cover the run line?

Using powerful machine learning and data analysis, we have simulated the result of Thursday's MLB game between the Rays and White Sox 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Rays a 53% chance of beating the White Sox.

According to our model, the White Sox (+1.5) have a 59% chance of covering the run line, while the 7.5-run over/under has a 53% chance of going over.

Rays vs. White Sox odds [9/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rays	White Sox
Run Line	-1.5 (+135)	+1.5 (-151)
Moneyline	-130	+110
Total	o7.5 (-120)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Rays vs. White Sox picks and best bets

Our model's biggest edge in today's Rays vs. White Sox matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Rays vs. White Sox game-day updates and essential details

Thursday's MLB action between the White Sox and Rays at Rate Field is scheduled to commence at 2:10PM ET.

• Who: Tampa Bay Rays vs. Chicago White Sox
• Date: Thursday, September 11, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: Rate Field

Dimers' in-depth preview of Thursday's Rays vs. White Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Rays vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Rays, with a 53% win probability, will likely beat the White Sox on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Rays vs. White Sox insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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