Rays vs. Cubs prediction: Why Cubs are favored to win Sunday's MLB matchup [9/14/2025]

The Chicago Cubs will take on the Tampa Bay Rays in MLB action at Wrigley Field on Sunday, commencing at 2:20PM ET.

The Cubs will send Shota Imanaga (9-7, 3.21 ERA) to the mound, up against Adrian Houser (8-4, 3.11 ERA) for the Rays.

Based on updated simulation results, Dimers' proven MLB model predicts the Cubs as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Rays-Cubs game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Cubs with a win probability of 60%, while the Rays have 40%."

For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive Rays vs. Cubs predictions page.

Cubs vs. Rays prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the outcome of Sunday's MLB matchup between the Rays and Cubs 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Cubs a 60% chance of defeating the Rays.

According to our model, the Rays (+1.5) have a 59% chance of covering the run line, while the 7-run over/under has a 55% chance of going over.

Rays vs. Cubs odds [9/14/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Rays	Cubs
Run Line	+1.5 (-164)	-1.5 (+138)
Moneyline	+140	-166
Total	o7 (+102)	u7 (-119)

All odds are correct at the time of publication and are subject to change.

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Rays vs. Cubs picks and best bets

Our model's strongest edge in today's Rays vs. Cubs matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Rays vs. Cubs game-day updates and essential details

Sunday's MLB action between the Cubs and Rays at Wrigley Field is scheduled to begin at 2:20PM ET.

• Who: Tampa Bay Rays vs. Chicago Cubs
• Date: Sunday, September 14, 2025
• Time: 2:20PM ET/11:20AM PT
• Venue: Wrigley Field

Dimers' comprehensive preview of Sunday's Rays vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Rays vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cubs, with a 60% win probability, will likely beat the Rays on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Rays vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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