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Rays vs. Orioles prediction: Close contest projected after new data released for Tuesday's MLB matchup [9/23/2025]

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Written by Jason Bevilacqua

Get Tampa Bay Rays vs Baltimore Orioles predictions for MLB Tuesday.

Tampa Bay Rays-Baltimore Orioles Predictions and Game Preview.
Tampa Bay Rays vs. Baltimore Orioles MLB prediction for Tuesday, September 23, 2025.

The Baltimore Orioles and Tampa Bay Rays are scheduled to meet in MLB action at Oriole Park at Camden Yards on Tuesday, starting at 6:35PM ET.

The Orioles will send Dean Kremer (10-10, 4.39 ERA) to the mound, pitting him against Ryan Pepiot (11-11, 3.77 ERA) for the Rays.

Based on updated simulations, Dimers' proven MLB model projects an equal chance for both the Orioles and Rays to win today's game.

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Rays vs. Orioles predictions page.

Orioles vs. Rays prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the result of Tuesday's MLB game between the Rays and Orioles 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently can't split the two teams, giving both the Rays and Orioles a 50% chance of winning the game.

According to our model, the Orioles (+1.5) have a 62% chance of covering the run line, while the 8.5-run over/under has a 57% chance of going over.

 

Rays vs. Orioles odds [9/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Rays Orioles
Run Line -1.5 (+164) +1.5 (-175)
Moneyline -104 -110
Total o8.5 (-106) u8.5 (-102)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Rays vs. Orioles picks and best bets

Our model's strongest edge in today's Rays vs. Orioles matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Rays vs. Orioles game-day updates and essential details

Tuesday's MLB game between the Orioles and Rays at Oriole Park at Camden Yards is scheduled to commence at 6:35PM ET.

Dimers' comprehensive preview of Tuesday's Rays vs. Orioles matchup includes our prediction, picks and the latest betting odds.

Before making any Rays vs. Orioles picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict a close game between the Rays and Orioles on Tuesday, with each team having a 50% chance of winning.

AI and automation have enhanced this article to quickly deliver accurate Rays vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate predictions for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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