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Rays vs. Orioles prediction: Baltimore favored to win Thursday's MLB matchup [9/25/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Tampa Bay Rays vs Baltimore Orioles predictions for MLB Thursday.
The Baltimore Orioles and Tampa Bay Rays will lock horns in MLB action at Oriole Park at Camden Yards on Thursday, starting at 1:05PM ET.
Cade Povich (3-8, 5.06 ERA) will start on the mound for the Orioles, while the Rays have opted for Drew Rasmussen (10-5, 2.80 ERA).
Based on updated simulation results, Dimers' advanced MLB model predicts the Orioles as the most likely winner of today's game.
For a closer look at Thursday's matchup, including best bets and picks, visit our interactive Rays vs. Orioles predictions page.
Orioles vs. Rays prediction: Who will win, cover the run line?
Using trusted machine learning and statistical analysis, we have simulated the result of Thursday's MLB matchup between the Rays and Orioles 10,000 times as part of our MLB predictions coverage.
Our independent predictive model currently gives the Orioles a 52% chance of defeating the Rays.
According to our model, the Orioles (+1.5) have a 64% chance of covering the run line, while the 8.5-run over/under has a 55% chance of going over.
Rays vs. Orioles odds [9/25/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Rays | Orioles |
|---|---|---|
| Run Line | -1.5 (+154) | +1.5 (-171) |
| Moneyline | -115 | +100 |
| Total | o8.5 (-103) | u8.5 (-110) |
All odds are correct at the time of publication and are subject to change.
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Rays vs. Orioles picks and best bets
Our model's strongest edge in today's Rays vs. Orioles matchup is on the run line.
Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's free ⚾️ picks
Calling Our Shot produces daily MLB betting content, including the predictions featured below.
Rays vs. Orioles game-day updates and essential details
Thursday's MLB action between the Orioles and Rays at Oriole Park at Camden Yards is scheduled to begin at 1:05PM ET.
- Who: Tampa Bay Rays vs. Baltimore Orioles
- Date: Thursday, September 25, 2025
- Time: 1:05PM ET/10:05AM PT
- Venue: Oriole Park at Camden Yards
Dimers' full preview of Thursday's Rays vs. Orioles matchup includes our prediction, picks and the latest betting odds.
Before making any Rays vs. Orioles picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Orioles, with a 52% win probability, will likely beat the Rays on Thursday.
AI and automation have enhanced this article to quickly deliver accurate Rays vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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