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Cardinals vs. Nationals Prediction: Washington Predicted to Win Sunday's MLB Matchup [5/11/2025]

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Written by Dave Garofolo

Our expert prediction for Sunday's St. Louis Cardinals vs Washington Nationals matchup.

St. Louis Cardinals-Washington Nationals Predictions and Game Preview.
Nationals Park sets the stage for the MLB matchup between the St. Louis Cardinals and Washington Nationals this Sunday.

The Washington Nationals and St. Louis Cardinals are scheduled to meet in MLB action at Nationals Park on Sunday, starting at 1:35PM ET.

MacKenzie Gore (2-3, 3.33 ERA) will be on the bump for the Nationals, up against Miles Mikolas (1-2, 4.76 ERA) for the Cardinals.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Nationals as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's St. Louis-Washington game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Nationals with a win probability of 60%, while the Cardinals have 40%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Cardinals vs. Nationals predictions page.

Nationals vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Sunday's MLB matchup between the Cardinals and Nationals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Nationals a 60% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 59% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

 

Cardinals vs. Nationals Odds [5/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Cardinals Nationals
Run Line +1.5 (-176) -1.5 (+150)
Moneyline +125 -142
Total o8.5 (-124) u8.5 (+102)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Cardinals vs. Nationals Picks and Best Bets

Our model's biggest edge in today's Cardinals vs. Nationals matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Cardinals vs. Nationals Game-Day Updates and Essential Details

Sunday's MLB game between the Nationals and Cardinals at Nationals Park is scheduled to start at 1:35PM ET.

Dimers.com's comprehensive preview of Sunday's Cardinals vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any St. Louis vs. Washington picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Nationals, with a 60% win probability, will likely beat the Cardinals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest predictions for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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