Cardinals vs. Pirates Prediction: Pittsburgh Predicted to Win Monday's MLB Matchup [6/30/2025]

MLB action continues on Monday at 6:40PM ET as the St. Louis Cardinals lock horns with the Pittsburgh Pirates at PNC Park.

The Pirates will start Andrew Heaney (3-7, 4.48 ERA), while the Cardinals have opted for Erick Fedde (3-7, 4.11 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Pirates as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Cardinals-Pirates game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Pirates are likely to win, with a probability of 51%, compared to the Cardinals' 49%."

For further insights into Monday's matchup, including best bets and picks, visit our interactive Cardinals vs. Pirates predictions page.

Pirates vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Cardinals and Pirates 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Pirates a 51% chance of defeating the Cardinals.

According to our model, the Pirates (+1.5) have a 64% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

Cardinals vs. Pirates Odds [6/30/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Pirates
Run Line	-1.5 (+155)	+1.5 (-180)
Moneyline	-104	-107
Total	o8.5 (-120)	u8.5 (+104)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Cardinals vs. Pirates matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Cardinals vs. Pirates Game-Day Updates and Essential Details

Monday's MLB action between the Pirates and Cardinals at PNC Park is scheduled to start at 6:40PM ET.

• Who: St. Louis Cardinals vs. Pittsburgh Pirates
• Date: Monday, June 30, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's comprehensive preview of Monday's Cardinals vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Cardinals vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pirates, with a 51% win probability, will likely beat the Cardinals on Monday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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