Cardinals vs. Phillies Prediction: Philadelphia Predicted to Win Monday's MLB Matchup [5/12/2025]

The Philadelphia Phillies will square off with the St. Louis Cardinals in MLB action at Citizens Bank Park on Monday, starting at 6:45PM ET.

The Phillies will have Cristopher Sánchez (4-1, 2.89 ERA) as their starting pitcher, while the Cardinals have opted for Matthew Liberatore (3-3, 3.07 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Phillies as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's St. Louis-Philadelphia game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Phillies are likely to win, with a probability of 61%, compared to the Cardinals' 39%."

For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Cardinals vs. Phillies predictions page.

Phillies vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Monday's MLB game between the Cardinals and Phillies 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Phillies a 61% chance of defeating the Cardinals.

According to our model, the Cardinals (+1.5) have a 57% chance of covering the run line, while the over/under total of 8.5 runs has a 51% chance of staying under.

Cardinals vs. Phillies Odds [5/12/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Phillies
Run Line	+1.5 (-135)	-1.5 (+125)
Moneyline	+152	-175
Total	o8.5 (-110)	u8.5 (-108)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Phillies Picks and Best Bets

Our model's biggest edge in today's Cardinals vs. Phillies matchup is on the total.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Cardinals vs. Phillies Game-Day Updates and Essential Details

Monday's MLB matchup between the Phillies and Cardinals at Citizens Bank Park is scheduled to commence at 6:45PM ET.

• Who: St. Louis Cardinals vs. Philadelphia Phillies
• Date: Monday, May 12, 2025
• Time: 6:45PM ET/3:45PM PT
• Venue: Citizens Bank Park

Dimers.com's in-depth preview of Monday's Cardinals vs. Phillies matchup includes our prediction, picks and the latest betting odds.

Before making any St. Louis vs. Philadelphia picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Phillies, with a 61% win probability, will likely beat the Cardinals on Monday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Phillies insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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