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Cardinals vs. Brewers Prediction: St. Louis Predicted to Win Thursday's MLB Matchup [6/12/2025]

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Written by Dave Garofolo

Our expert prediction for Thursday's St. Louis Cardinals vs Milwaukee Brewers matchup.

St. Louis Cardinals-Milwaukee Brewers Predictions and Game Preview.
American Family Field sets the stage for the MLB matchup between the St. Louis Cardinals and Milwaukee Brewers this Thursday.

The Milwaukee Brewers and St. Louis Cardinals will meet in MLB action at American Family Field on Thursday, starting at 7:40PM ET.

Jacob Misiorowski (0-0, 0.00 ERA) will get the ball for the Brewers, pitting him against Sonny Gray (7-1, 3.34 ERA) for the Cardinals.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's St. Louis-Milwaukee game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Cardinals with a win probability of 53% and the Brewers with 47%."

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Cardinals vs. Brewers predictions page.

Brewers vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the outcome of Thursday's MLB game between the Cardinals and Brewers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Cardinals a 53% chance of defeating the Brewers.

According to our model, the Brewers (+1.5) have a 62% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of staying under.

 

Cardinals vs. Brewers Odds [6/12/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Cardinals Brewers
Run Line -1.5 (+133) +1.5 (-146)
Moneyline -133 +115
Total o7.5 (-105) u7.5 (-108)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Cardinals vs. Brewers Picks and Best Bets

Our model's strongest edge in today's Cardinals vs. Brewers matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Cardinals vs. Brewers Game-Day Updates and Essential Details

Thursday's MLB game between the Brewers and Cardinals at American Family Field is scheduled to commence at 7:40PM ET.

Dimers.com's in-depth preview of Thursday's Cardinals vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any St. Louis vs. Milwaukee picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Cardinals, with a 53% win probability, will likely beat the Brewers on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest projections for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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