Cardinals vs. Rockies Prediction: St. Louis Predicted to Win Wednesday's MLB Matchup [7/23/2025]

The Colorado Rockies will square off with the St. Louis Cardinals in MLB action at Coors Field on Wednesday, starting at 3:10PM ET.

Tanner Gordon (1-2, 4.24 ERA) will be the starting pitcher for the Rockies, up against Andre Pallante (5-6, 4.71 ERA) for the Cardinals.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Cardinals-Rockies game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cardinals' chance of winning at 60%, with the Rockies at 40%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Cardinals vs. Rockies predictions page.

Rockies vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Wednesday's MLB matchup between the Cardinals and Rockies 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Cardinals a 60% chance of beating the Rockies.

According to our model, the bookmakers have got it right, and the Cardinals and Rockies each have a 50% chance of covering the run line, while the over/under total of 11 runs has a 53% chance of staying under.

Cardinals vs. Rockies Odds [7/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Rockies
Run Line	-1.5 (-122)	+1.5 (+105)
Moneyline	-186	+156
Total	o11 (-110)	u11 (-105)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Rockies Picks and Best Bets

Our model's strongest edge in today's Cardinals vs. Rockies matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Cardinals vs. Rockies Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Rockies and Cardinals at Coors Field is scheduled to begin at 3:10PM ET.

• Who: St. Louis Cardinals vs. Colorado Rockies
• Date: Wednesday, July 23, 2025
• Time: 3:10PM ET/12:10PM PT
• Venue: Coors Field

Dimers.com's in-depth preview of Wednesday's Cardinals vs. Rockies matchup includes our prediction, picks and the latest betting odds.

Before making any Cardinals vs. Rockies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Plus, with sports betting in Missouri set to launch on December 1, 2025, Dimers has you covered with the latest updates and the best pre-registration offers in MO.

Conclusion

We predict the Cardinals, with a 60% win probability, will likely beat the Rockies on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Rockies insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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