Cardinals vs. Reds Prediction: Cincinnati Predicted to Win Thursday's MLB Matchup [5/1/2025]

The Cincinnati Reds will take on the St. Louis Cardinals in MLB action at Great American Ball Park on Thursday, beginning at 12:40PM ET.

The Reds will start Andrew Abbott (2-0, 3.60 ERA), while the Cardinals have opted for Matthew Liberatore (2-2, 3.19 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Reds as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's St. Louis-Cincinnati game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Reds with a win probability of 53% and the Cardinals with 47%."

For further insights into Thursday's matchup, including best bets and picks, visit our interactive Cardinals vs. Reds predictions page.

Reds vs. Cardinals Prediction: Who Will Win?

Using innovative machine learning and data, we have simulated the outcome of Thursday's MLB matchup between the Cardinals and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Reds a 53% chance of defeating the Cardinals.

According to our model, the over/under total of 9 runs has a 55% chance of staying under.

Cardinals vs. Reds Odds [5/1/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Reds
Moneyline	-112	+100
Total	o9 (-102)	u9 (-110)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Reds Picks and Best Bets

Our model's biggest edge in today's Cardinals vs. Reds matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Cardinals vs. Reds Game-Day Updates and Essential Details

Thursday's MLB action between the Reds and Cardinals at Great American Ball Park is scheduled to begin at 12:40PM ET.

• Who: St. Louis Cardinals vs. Cincinnati Reds
• Date: Thursday, May 1, 2025
• Time: 12:40PM ET/9:40AM PT
• Venue: Great American Ball Park

Dimers.com's full preview of Thursday's Cardinals vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any St. Louis vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Reds, with a 53% win probability, will likely beat the Cardinals on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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