...
...
Read Article
Cardinals vs. Orioles Prediction: Baltimore Predicted to Win Monday's MLB Matchup [5/26/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Monday's St. Louis Cardinals vs Baltimore Orioles matchup.
The Baltimore Orioles will square off with the St. Louis Cardinals, in what is expected to be a tight MLB game, at Oriole Park at Camden Yards on Monday, beginning at 3:05PM ET.
The Orioles will send Charlie Morton (0-7, 7.68 ERA) to the mound, while the Cardinals will counter with Erick Fedde (3-3, 3.77 ERA).
Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Orioles as the most likely winner of today's game.
"Our team has utilized the latest data to simulate Monday's St. Louis-Baltimore game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"Incorporating recent updates and thousands of additional inputs, our prediction shows the Orioles are likely to win, with a probability of 52%, compared to the Cardinals' 48%."
For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Cardinals vs. Orioles predictions page.
Orioles vs. Cardinals Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the result of Monday's MLB matchup between the Cardinals and Orioles 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Orioles a 52% chance of beating the Cardinals.
According to our model, the Orioles (+1.5) have a 64% chance of covering the run line, while the 9-run over/under has a 53% chance of staying under.
Cardinals vs. Orioles Odds [5/26/2025]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Cardinals | Orioles |
|---|---|---|
| Run Line | -1.5 (+146) | +1.5 (-170) |
| Moneyline | -115 | +100 |
| Total | o9 (+100) | u9 (-115) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Cardinals vs. Orioles Picks and Best Bets
Our model's biggest edge in today's Cardinals vs. Orioles matchup is on the moneyline.
Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free MLB Picks
Calling Our Shot produces daily MLB betting content, including the free picks featured below.
Cardinals vs. Orioles Game-Day Updates and Essential Details
Monday's MLB action between the Orioles and Cardinals at Oriole Park at Camden Yards is scheduled to begin at 3:05PM ET.
- Who: St. Louis Cardinals vs. Baltimore Orioles
- Date: Monday, May 26, 2025
- Time: 3:05PM ET/12:05PM PT
- Venue: Oriole Park at Camden Yards
Dimers.com's in-depth preview of Monday's Cardinals vs. Orioles matchup includes our prediction, picks and the latest betting odds.
Before making any St. Louis vs. Baltimore picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
- Understand where sports odds come from and how they're applied to baseball matchups
- Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
- Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on
Conclusion
We predict the Orioles, with a 52% win probability, will likely beat the Cardinals on Monday.
AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
More on MLB
Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest probabilities for the World Series, American League, National League and each division.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
Advertiser disclosure