Cardinals vs. Diamondbacks Prediction: St. Louis Predicted to Win Saturday's MLB Matchup [7/19/2025]

The Arizona Diamondbacks will take on the St. Louis Cardinals, in what is expected to be a close MLB game, at Chase Field on Saturday, commencing at 7:15PM ET.

Ryne Nelson (5-2, 3.68 ERA) will start on the mound for the Diamondbacks, up against Sonny Gray (9-3, 3.50 ERA) for the Cardinals.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Cardinals as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Cardinals vs. Diamondbacks predictions page.

Diamondbacks vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Saturday's MLB matchup between the Cardinals and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Cardinals a 54% chance of defeating the Diamondbacks.

According to our model, the Diamondbacks (+1.5) have a 60% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

Cardinals vs. Diamondbacks Odds [7/19/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Diamondbacks
Run Line	-1.5 (+135)	+1.5 (-152)
Moneyline	-132	+115
Total	o8.5 (+100)	u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Diamondbacks Picks and Best Bets

Our model's strongest edge in today's Cardinals vs. Diamondbacks matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Cardinals vs. Diamondbacks Game-Day Updates and Essential Details

Saturday's MLB matchup between the Diamondbacks and Cardinals at Chase Field is scheduled to start at 7:15PM ET.

• Who: St. Louis Cardinals vs. Arizona Diamondbacks
• Date: Saturday, July 19, 2025
• Time: 7:15PM ET/4:15PM PT
• Venue: Chase Field

Dimers.com's comprehensive preview of Saturday's Cardinals vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Cardinals vs. Diamondbacks picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cardinals, with a 54% win probability, will likely beat the Diamondbacks on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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