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North QLD Cowboys vs. St George Illawarra Dragons Prediction: Cowboys Predicted to Win Friday's NRL Round 21 Matchup [7/25/2025]
Updated: | First published:
Written by Damien Souness, Chief Innovation Officer
Our expert prediction for Friday's North QLD Cowboys vs St George Illawarra Dragons matchup.
The North QLD Cowboys will take on the St George Illawarra Dragons in National Rugby League (NRL) action at Queensland Country Bank Stadium on Friday, beginning at 4:00AM ET.
Based on the latest simulation results, Dimers' proven NRL model (see Dimers Pro for full access) predicts the Cowboys as the most likely winner of today's game.
For a closer look at Friday's matchup, including best bets and picks, visit our interactive Dragons vs. Cowboys predictions page.
Cowboys vs. Dragons Prediction: Who Will Win Round 21 Game?
Using powerful machine learning and data analysis, we have simulated the result of Friday's NRL game between the Dragons and Cowboys 10,000 times as part of our NRL predictions coverage.
Our independent predictive model gives the Cowboys a 66% chance of defeating the Dragons.
According to our model, the Cowboys (-2.5) have a 56% chance of covering the spread, while the over/under total of 49.5 has a 58% chance of staying under.
St George vs. Cowboys Odds
We have researched the best NRL odds in America for this game, which are listed here:
| Bet Type | Dragons | Cowboys |
|---|---|---|
| H2H (Moneyline) | +118 | -152 |
| Line (Spread) | +2.5 (-115) | -2.5 (-110) |
| Total | o49.5 (-120) | u49.5 (-106) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Cowboys vs. Dragons Game-Day Updates and Essential Details
Friday's Australian rugby league matchup between the Cowboys and Dragons at Queensland Country Bank Stadium is scheduled to commence at 4:00AM ET.
- Who: St George Illawarra Dragons vs. North QLD Cowboys
- Date: Friday, July 25, 2025
- Time: 4:00AM ET/1:00AM PT
- Venue: Queensland Country Bank Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Dimers.com's full preview of Friday's Dragons vs. Cowboys matchup includes our prediction, picks and the latest betting odds.
Before making any St George vs. Cowboys picks, be sure to check out the latest NRL predictions and betting advice from Dimers Pro.
Conclusion
We predict the Cowboys, with a 66% win probability, will likely beat the Dragons on Friday.
AI and automation have enhanced this article to quickly deliver accurate Dragons vs. Cowboys insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.
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