Southern University vs. Fresno State prediction: Fresno State favored to win in college football Week 3, 2025

Fresno State will face Southern University in Week 3 college football action at Valley Children's Stadium on Saturday, commencing at 10:00PM ET.

Based on updated simulation results, Dimers' proven college football model projects Fresno State as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Southern University vs. Fresno State predictions page.

Southern University vs. Fresno State prediction: Who will win, cover the spread?

Using powerful machine learning and statistical analysis, we have simulated the result of Southern University vs. Fresno State 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Fresno State a 100% chance of defeating Southern University. Our predicted final score has Fresno State winning 43-5.

According to our model, the bookies have got it right, and Southern University and Fresno State each have a 50% chance of covering the spread, while the over/under total of 51.5 points also has an equal 50-50 chance of hitting.

Southern University vs. Fresno State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Southern University	Fresno State
Spread	+37.5 (-106)	-37.5 (-110)
Moneyline	+8000	-100000
Total	o51.5 (-106)	u51.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Southern University vs. Fresno State picks and best bets

Our model's biggest edge in today's Southern University vs. Fresno State matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Southern University vs. Fresno State game-day updates and essential details

Saturday's college football action between Fresno State and Southern University at Valley Children's Stadium is scheduled to start at 10:00PM ET.

• Who: Southern University vs. Fresno State
• Date: Saturday, September 13, 2025
• Time: 10:00PM ET/7:00PM PT
• Venue: Valley Children's Stadium

Dimers' in-depth preview of Saturday's Southern University vs. Fresno State matchup includes our prediction, picks and the latest betting odds.

Before making any Southern University vs. Fresno State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Fresno State, with a 100% win probability, will likely beat Southern University on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Southern University vs. Fresno State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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