Southeast Missouri State vs. Tennessee-Martin prediction: Why Southeast Missouri State is favored to win in college football Week 5, 2025

Tennessee-Martin and Southeast Missouri State will meet in Week 5 college football action at Hardy M. Graham Stadium on Saturday, starting at 7:00PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts Southeast Missouri State as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Southeast Missouri State vs. Tennessee-Martin predictions page.

Southeast Missouri State vs. Tennessee-Martin prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Southeast Missouri State vs. Tennessee-Martin 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Southeast Missouri State a 52% chance of defeating Tennessee-Martin. Our predicted final score has Southeast Missouri State winning 28-27.

According to our model, Tennessee-Martin (+3.5) has a 60% chance of covering the spread, while the over/under total of 56.5 points has a 51% chance of going over.

Southeast Missouri State vs. Tennessee-Martin odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Southeast Missouri State	Tennessee-Martin
Spread	-3.5 (-110)	+3.5 (-110)
Moneyline	-155	+138
Total	o56.5 (-110)	u56.5 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Southeast Missouri State vs. Tennessee-Martin picks and best bets

Our model's biggest edge in today's Southeast Missouri State vs. Tennessee-Martin matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Southeast Missouri State vs. Tennessee-Martin game-day updates and essential details

Saturday's college football matchup between Tennessee-Martin and Southeast Missouri State at Hardy M. Graham Stadium is scheduled to begin at 7:00PM ET.

• Who: Southeast Missouri State vs. Tennessee-Martin
• Date: Saturday, September 27, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Hardy M. Graham Stadium

Dimers' full preview of Saturday's Southeast Missouri State vs. Tennessee-Martin matchup includes our prediction, picks and the latest betting odds.

Before making any Southeast Missouri State vs. Tennessee-Martin picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict Southeast Missouri State, with a 52% win probability, will likely beat Tennessee-Martin on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Southeast Missouri State vs. Tennessee-Martin insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Keep up with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the most up-to-date projections for the national title game and major conferences.