Southampton vs. Tottenham Predictions and Odds - Dec 28, 2021

Southampton takes on Tottenham in Premier League action at St. Mary's Stadium on Tuesday, beginning at 10:00AM EST.

Dimers' top betting tips for Southampton vs. Tottenham, plus match predictions and best odds, are detailed in this article.

Who will win Southampton vs. Tottenham?

Using cutting-edge machine learning and data, Dimers.com has simulated Tuesday's Southampton-Tottenham Premier League match 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives Southampton a 24.4% chance of winning, Tottenham a 52.6% chance of winning, and the draw a 23.0% chance of happening.

MORE: Southampton vs. Tottenham Simulated 10K Times

Moneyline and Over/Under

FanDuel Sportsbook has the best moneyline odds for Southampton at +270. That means you can throw down $100 to profit $270, earning a total payout of $370, if it wins.

On the other hand, BetMGM has the best moneyline odds for Tottenham at +105, where you can bet $100 to profit $105, earning a total payout of $205, if it wins.

Lastly, BetMGM has the best odds for the draw at +250, which means you can bet $100 to win $250, for a total payout of $350, if it hits.

The Over/Under is set at 2.5 with Caesars Sportsbook, which has the best odds for the Over at -115, while FanDuel Sportsbook has the best odds for the Under at +104.

As always, check out all the online sportsbooks available in your state for the best Premier League odds and lines.

According to DimersBOT, the Over/Under total of 2.5 goals is a 57% chance of going Over.

MORE: Predictions for Every Premier League Match

Best Bets for Southampton vs. Tottenham

• Moneyline: Tottenham Win at +105 with BetMGM (53% probability)
• Over/Under: Over 2.5 at -115 with Caesars Sportsbook (57% probability)

Southampton vs. Tottenham Probabilities

Use our interactive widget below to see the current Moneyline, Correct Score and Over/Under probabilities and odds for the match, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Tuesday's Southampton-Tottenham match, including pre-game predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this page for the latest betting analysis before Southampton vs. Tottenham on Tuesday December 28, 2021.

Best Sportsbook Promo for Southampton vs. Tottenham

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Southampton vs. Tottenham 2021 Match Info

What time does Southampton vs. Tottenham start in USA?

• Date: Tuesday December 28, 2021
• Time: 10:00AM EST / 7:00AM PST
• Venue: St. Mary's Stadium

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Want more Premier League analysis like this?

So, you liked our Southampton vs. Tottenham betting analysis? Awesome. Did you know our Premier League Betting News page has a comprehensive betting preview for every English Premier League matchup as soon as the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to create the most accurate Premier League betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not take a look around?