Premier League- More Betting
Southampton vs. Manchester City Predictions and Odds - Jan 22, 2022

Premier League action continues on Saturday at 12:30PM EST as the favored Manchester City locks horns with Southampton at St. Mary's Stadium.
Dimers' top betting tips for Southampton vs. Manchester City, as well as match predictions and best odds, are detailed in this article.
Who will win Manchester City vs. Southampton?
Using state-of-the-art machine learning and data, Dimers.com has simulated Saturday's Southampton-Manchester City Premier League match 10,000 times.
Dimers' leading predictive analytics model, DimersBOT, gives Southampton a 6.7% chance of winning, Manchester City a 79.2% chance of winning, and the draw a 14.1% chance of happening.
MORE: Southampton vs. Manchester City Simulated 10K Times
Moneyline and Over/Under
FanDuel Sportsbook currently has the best moneyline odds for Southampton at +1000. That means you can bet $100 to profit $1,000, earning a total payout of $1,100, if it wins.
Meanwhile, FanDuel Sportsbook also has the best moneyline odds for Manchester City at -370, where you can risk $370 to win $100, for a total payout of $470, if it comes out on top.
Lastly, BetMGM currently has the best odds for the draw at +500, which means you can bet $100 to win $500, for a total payout of $600, if it hits.
The Over/Under for total goals scored sits at 2.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -174, as well as the best odds for the Under at +142.
As always, check out the sportsbooks you have access to in your state for the best Premier League odds and lines.
According to DimersBOT, the 2.5-goal Over/Under is a 60% chance of going Over.
MORE: Today's Best Bets for All Major Sports
Best Bets for Southampton vs. Manchester City
- Moneyline: Manchester City at -370 with FanDuel Sportsbook (79% probability)
- Over/Under: Under 2.5 at +142 with FanDuel Sportsbook
Dimers' best bets are based on detailed simulations and wagering intelligence to bring you the best possible plays every time.
Despite the Over being more likely to hit on this occasion, Under 2.5 is our best bet owing to the better odds (+142) that are available from FanDuel Sportsbook.
Manchester City vs. Southampton Betting Guide
Use our widget below to explore the latest Moneyline, Correct Score and Over/Under probabilities and odds for the match, and click or tap on See Matchup for more.
Dimers has full coverage of Saturday's Southampton-Manchester City match, including pre-game predictions, computer picks, and live win probabilities.
Remember, DimersBOT updates frequently, so keep checking this page for any changes to our betting analysis before Southampton vs. Manchester City on Saturday January 22, 2022.
Get a Risk-Free Bet for Southampton vs. Manchester City
Do you want to bet on Southampton vs. Manchester City? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Saturday's match.
All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.
Then, make your first deposit and place a bet up to $1K on Southampton vs. Manchester City. If you don't win your bet, FanDuel Sportsbook will give it back to you in site credit!
This offer is available to all new FanDuel Sportsbook users – no promo code required!
Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.
Southampton vs. Manchester City 2022 Match Info
What time does Southampton vs. Manchester City start in the United States?
- Date: Saturday January 22, 2022
- Time: 12:30PM EST / 9:30AM PST
- Venue: St. Mary's Stadium
Looking to join an online sportsbook and start betting on ⚽️ in the United States now? We've reviewed the best available sign-up offers in every legal betting state.
Want more Premier League analysis like this?
So, you liked our Southampton vs. Manchester City betting predictions? Awesome. Did you know our Premier League Betting News section has a comprehensive betting preview for every English Premier League matchup as soon as the sportsbooks put out their odds?
That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to produce the most accurate Premier League betting previews and get the jump on the public and the sportsbooks.
It's only a click away, so why not see for yourself?