Mariners vs. Padres Prediction: San Diego Predicted to Win Sunday's MLB Matchup [5/18/2025]

MLB action continues on Sunday at 4:10PM ET as the Seattle Mariners square off with the San Diego Padres at PETCO Park.

The Padres will have Michael King (4-1, 2.32 ERA) as their starting pitcher, up against Bryan Woo (4-1, 2.84 ERA) for the Mariners.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Padres as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Seattle-San Diego game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Padres with a win probability of 60%, while the Mariners have 40%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Mariners vs. Padres predictions page.

Padres vs. Mariners Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Sunday's MLB matchup between the Mariners and Padres 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Padres a 60% chance of defeating the Mariners.

According to our model, the Mariners (+1.5) have a 60% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of staying under.

Mariners vs. Padres Odds [5/18/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Mariners	Padres
Run Line	+1.5 (-180)	-1.5 (+155)
Moneyline	+124	-142
Total	o7.5 (-105)	u7.5 (-114)

All odds are correct at the time of publication and are subject to change.

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Mariners vs. Padres Picks and Best Bets

Our model's biggest edge in today's Mariners vs. Padres matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Mariners vs. Padres Game-Day Updates and Essential Details

Sunday's MLB game between the Padres and Mariners at PETCO Park is scheduled to commence at 4:10PM ET.

• Who: Seattle Mariners vs. San Diego Padres
• Date: Sunday, May 18, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: PETCO Park

Dimers.com's comprehensive preview of Sunday's Mariners vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Seattle vs. San Diego picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Padres, with a 60% win probability, will likely beat the Mariners on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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