Mariners vs. Twins Prediction: Minnesota Predicted to Win Wednesday's MLB Matchup [6/25/2025]

The Minnesota Twins and Seattle Mariners will meet in MLB action at Target Field on Wednesday, starting at 7:40PM ET.

The Twins will start Joe Ryan (7-3, 3.06 ERA), up against George Kirby (1-3, 6.16 ERA) for the Mariners.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Twins as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Mariners-Twins game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Twins' chance of winning at 55%, with the Mariners at 45%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Mariners vs. Twins predictions page.

Twins vs. Mariners Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Mariners and Twins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Twins a 55% chance of beating the Mariners.

According to our model, the Mariners (+1.5) have a 64% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of going over.

Mariners vs. Twins Odds [6/25/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Mariners	Twins
Run Line	+1.5 (-225)	-1.5 (+170)
Moneyline	+102	-120
Total	o7.5 (-105)	u7.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Mariners vs. Twins Picks and Best Bets

Our model's strongest edge in today's Mariners vs. Twins matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Mariners vs. Twins Game-Day Updates and Essential Details

Wednesday's MLB game between the Twins and Mariners at Target Field is scheduled to begin at 7:40PM ET.

• Who: Seattle Mariners vs. Minnesota Twins
• Date: Wednesday, June 25, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Target Field

Dimers.com's in-depth preview of Wednesday's Mariners vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any Mariners vs. Twins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Twins, with a 55% win probability, will likely beat the Mariners on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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