Mariners vs. Astros Prediction: Seattle Predicted to Win Sunday's MLB Matchup [5/25/2025]

MLB action continues on Sunday at 2:10PM ET as the Seattle Mariners square off with the Houston Astros at Daikin Park.

The Astros will send Colton Gordon (0-0, 5.59 ERA) to the mound, up against Luis Castillo (4-3, 3.20 ERA) for the Mariners.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Mariners as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Seattle-Houston game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Mariners with a win probability of 52%, while the Astros have 48%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Mariners vs. Astros predictions page.

Astros vs. Mariners Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Sunday's MLB matchup between the Mariners and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Mariners a 52% chance of beating the Astros.

According to our model, the Astros (+1.5) have a 62% chance of covering the run line, while the over/under total of 8.5 runs has a 53% chance of staying under.

Mariners vs. Astros Odds [5/25/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Mariners	Astros
Run Line	-1.5 (+125)	+1.5 (-135)
Moneyline	-144	+124
Total	o8.5 (-102)	u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Mariners vs. Astros Picks and Best Bets

Our model's biggest edge in today's Mariners vs. Astros matchup is on the total.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Mariners vs. Astros Game-Day Updates and Essential Details

Sunday's MLB matchup between the Astros and Mariners at Daikin Park is scheduled to begin at 2:10PM ET.

• Who: Seattle Mariners vs. Houston Astros
• Date: Sunday, May 25, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: Daikin Park

Dimers.com's comprehensive preview of Sunday's Mariners vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Seattle vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Mariners, with a 52% win probability, will likely beat the Astros on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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