Mariners vs. Guardians prediction: Why Seattle is favored to win Friday's MLB matchup [8/29/2025]

The Cleveland Guardians will face the Seattle Mariners in MLB action at Progressive Field on Friday, starting at 7:10PM ET.

Logan Allen (7-10, 4.35 ERA) will be the starting pitcher for the Guardians, while the Mariners are going with George Kirby (8-6, 4.04 ERA).

Based on the latest simulations, Dimers' advanced MLB model predicts the Mariners as the most likely winner of today's game.

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Mariners vs. Guardians predictions page.

Guardians vs. Mariners prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the outcome of Friday's MLB matchup between the Mariners and Guardians 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Mariners a 58% chance of defeating the Guardians.

According to our model, the Guardians (+1.5) have a 56% chance of covering the run line, while the 7.5-run over/under has a 57% chance of going over.

Mariners vs. Guardians odds [8/29/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Mariners	Guardians
Run Line	-1.5 (+118)	+1.5 (-127)
Moneyline	-160	+136
Total	o7.5 (-118)	u7.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Mariners vs. Guardians picks and best bets

Our model's strongest edge in today's Mariners vs. Guardians matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Mariners vs. Guardians game-day updates and essential details

Friday's MLB matchup between the Guardians and Mariners at Progressive Field is scheduled to begin at 7:10PM ET.

• Who: Seattle Mariners vs. Cleveland Guardians
• Date: Friday, August 29, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Progressive Field

Dimers.com's comprehensive preview of Friday's Mariners vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Mariners vs. Guardians picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Mariners, with a 58% win probability, will likely beat the Guardians on Friday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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