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Santos Laguna vs. Guadalajara Prediction, Odds, Liga MX Picks [8/10/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Our expert prediction for Sunday's Santos Laguna vs Guadalajara matchup.
Santos Laguna will face Guadalajara in Liga MX action at Estadio Corona on Sunday, starting at 10:05PM ET.
Based on updated simulation results, Dimers' advanced Liga MX model (see Dimers Pro for full access) projects Guadalajara as the most likely winner of today's game. "Using the most recent data, our experts ran 10,000 simulations of Sunday's Santos Laguna-Guadalajara game," said Dave Garofolo from Dimers.
"Taking into account the most current updates and numerous additional factors, our prediction gives Santos Laguna a 21.0% chance of winning, Guadalajara a 55.2% chance, and a 23.8% chance of a draw."
For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive Santos Laguna vs. Guadalajara predictions page.
Santos Laguna vs. Guadalajara Prediction: Who Will Win?
Using trusted machine learning and statistical analysis, we have simulated the result of Sunday's Liga MX matchup between Santos Laguna and Guadalajara 10,000 times as part of our Liga MX predictions coverage.
Our leading predictive model currently suggests a 21.0% chance of Santos Laguna winning, a 55.2% chance for Guadalajara, and a 23.8% chance of a draw.
Additionally, the 2.5-goal over/under also has an equal 50-50 chance of hitting, according to our model.
Santos Laguna vs. Guadalajara Odds
We have sourced the best Liga MX odds in America for this game, which are listed here:
Moneyline
| Santos Laguna | Guadalajara | Draw |
|---|---|---|
| +410 | -145 | +300 |
Total Goals
| Over 2.5 | Under 2.5 |
|---|---|
| -142 | +116 |
All odds are correct at the time of publication and are subject to change.
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Santos Laguna vs. Guadalajara Picks and Best Bets
Our model's biggest edge in today's Santos Laguna vs. Guadalajara matchup is on the total.
Our expert predictions, matched against the current odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Santos Laguna vs. Guadalajara: Correct Score and BTTS Predictions
Here are the top three most likely final scores according to our model, with a 1-0 Guadalajara win being the most probable:
| Final Score | Probability |
|---|---|
| SLA 0-1 GUA | 11.8% |
| SLA 1-1 GUA | 11.3% |
| SLA 0-2 GUA | 10.1% |
When it comes to the both teams to score (BTTS) market, we project a 50.7% chance that both Santos Laguna and Guadalajara score, and a 49.3% probability of at least one team being held goalless.
These predictions are based on each team's average score after 10,000 simulations.
Santos Laguna vs. Guadalajara Game-Day Updates and Essential Details
Sunday's matchup between Santos Laguna and Guadalajara at Estadio Corona is scheduled to start at 10:05PM ET.
- Who: Santos Laguna vs. Guadalajara
- Date: Sunday, August 10, 2025
- Time: 10:05PM ET/7:05PM PT
- Venue: Estadio Corona
Dimers.com's comprehensive preview of Sunday's Santos Laguna vs. Guadalajara matchup includes our prediction, picks and the latest betting odds.
Before making any Guadalajara vs. Santos Laguna picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.
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Conclusion
According to our computer model, Santos Laguna has a 21.0% win probability on Sunday, Guadalajara has a 55.2% win probability, and there is a 23.8% chance that the game will end in a draw.
AI and automation have enhanced this article to quickly deliver accurate Santos Laguna vs. Guadalajara insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on Liga MX
Stay informed with the latest Liga MX betting news and parlay picks throughout the season.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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