San Jose Earthquakes vs. St Louis City prediction, odds, picks, and MLS Season Pass discount code [9/20/2025]

MLS action continues on Saturday at 10:30PM ET as St Louis City squares off with San Jose at PayPal Park in San Jose, California.

Based on updated simulation results, Dimers' proven MLS model predicts San Jose as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive San Jose vs. St Louis City predictions page.

San Jose Earthquakes vs. St Louis City prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Saturday's MLS game between San Jose and St Louis City 10,000 times as part of our MLS predictions coverage.

Our independent predictive model currently suggests a 56.5% chance of San Jose winning, a 23.8% chance for St Louis City, and a 19.7% chance of a draw.

San Jose Earthquakes vs. St Louis City odds

We have sourced the best MLS odds in America for this game, which are listed here:

Market	San Jose	St Louis City	Draw
Moneyline	-140	+300	+330

All odds are correct at the time of publication and are subject to change.

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San Jose Earthquakes vs. St Louis City picks and best bets

Our model's biggest edge in today's San Jose Earthquakes vs. St Louis City matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLS picks and MLS best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

San Jose Earthquakes vs. St Louis City: Correct score predictions

Here are the top three most likely final scores according to our model, with a 2-1 San Jose win being the most probable:

Final Score	Probability
SJE 2-1 STL	9%
SJE 1-1 STL	7.7%
SJE 3-1 STL	6.9%

These predictions are based on each team's average score after 10,000 simulations.

San Jose Earthquakes vs. St Louis City game-day updates and essential details

Saturday's matchup between San Jose and St Louis City in MLS at PayPal Park is scheduled to begin at 10:30PM ET.

• Who: San Jose Earthquakes vs. St Louis City
• Date: Saturday, September 20, 2025
• Time: 10:30PM ET/7:30PM PT
• Venue: PayPal Park (San Jose, California)

Dimers' full preview of Saturday's San Jose vs. St Louis City matchup includes our prediction, picks and the latest betting odds.

Before making any St Louis City vs. San Jose picks, be sure to check out the latest MLS predictions and betting advice from Dimers Pro.

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Conclusion

According to our computer model, San Jose has a 56.5% win probability on Saturday, St Louis City has a 23.8% win probability, and there is a 19.7% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate San Jose vs. St Louis City insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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